Journal: Cell metabolism
Article Title: A blood-based biomarker panel for non-invasive diagnosis of metabolic dysfunction-associated steatohepatitis.
doi: 10.1016/j.cmet.2024.10.008
Figure Lengend Snippet: Figure 2. Performance of N3-MASH for diag- nosis of MASLD in the discovery and valida- tion cohort (A and B) ROC curve for N3-MASH and individual protein markers (CXCL10 and CK-18) in discrimi- nating MASLD from healthy controls in the discovery cohort from Hong Kong, China, by logistic regression (A) and SVM (B). (C and D) ROC curve for N3-MASH and individual protein markers (CXCL10 and CK-18) in discrimi- nating MASH from patients with MASL in the vali- dation cohort from San Diego, USA, by logistic regression (C) and SVM (D). See also Figures S1, S2, and S4 and Tables S2 and S3.
Article Snippet: Serum levels of CK-18, FGF21, CXCL10, P62, SQLE, and CA3 were measured by PEVIVA M30-Apoptosense enzyme-linked immunosorbent assay (ELISA) kit (P10011, DiaPharma Group, West Chester, OH), human CXCL10 immunoassay ELISA kit (DIP100, R&D company, Minneapolis, MN), human FGF21 ELISA kit (DF2100, R&D company), human p62/SQSTM1 ELISA Kit (#SED198Hu, Cloud-Clone Corp, Wuhan, China), human SQLE ELISA kit (#SEH135Hu, Cloud-Clone Corp), and human CA3 ELISA kit (#SED070Hu, CloudClone Corp), respectively.
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